Publications

2018

  • Linking Genomic and Metabolomic Natural Variation Uncovers Nematode Pheromone Biosynthesis.
    JM Falcke, N Bose, AB Artyukhin, C Rödelsperger, GV Markov JJ Yim, DG Grimm, MH Claassen, O Panda, JA Baccile, YK Zhang, HH Le, D Jolic, FC Schroeder, RJ SommerCell Chemical Biology, 2018 (Link)
  • Exosome-based Detection of EGFR T790M in Plasma from Non-Small Cell Lung Cancer Patients.
    E Castellanos-Rizaldos, DG Grimm, V Tadigotla, J Hurley, J Healy, PL Neal, M Sher, R Venkatesan, C Karlovich, M Raponi, AK Krug, M Noerholm, J Tannous, BA Tannous, LE Real, J Skog
    Clinical Cancer Research (CCR), 2018 (Link)
  • The AraGWAS Catalog: A curated and standardized Arabidopsis thaliana GWAS catalog
    M Togninalli*, Ü Seren*, M Dazhe, F Joffrey, M Nordborg, D Weigel, KM Borgwardt, A Korte and DG Grimm
    Nucleic Acid Research (NAR), 2018 (Link)
    * Contributed equally
  • The rate and potential relevance of new mutations in a colonizing plant lineage
    M Exposito-Alonso*, C Becker*, VJ Schuenemann, E Reiter, C Setzer, R Slovak, B Brachi, J Hagmann, DG Grimm, J Chen, W Busch, J Bergelson, RW Ness, J Krause, HA Burbano, D Weigel
    PLoS Genetics, 2018 (Link)
    * Contributed equally

2017

  • Improved EGFR mutation detection using combined exosomal RNA and circulating tumor DNA in NSCLC patient plasma
    K Krug, D Enderle, C Karlovich, T Priewasser, S Bentink, A Spiel, K Brinkmann, J Emenegger, DG Grimm, E Castellanos-Rizaldos, JW Goldman, LV Sequist, J-C Soria, DR Camidge, SM Gadgeel, HA Wakelee, M Raponi, M Noerholm, J Skog
    Annals of Oncology, 2017, mdx765 (Link)
  • easyGWAS: A cloud-based platform for comparing the results of genome-wide association studies.
    DG Grimm, D Roqueiro, PA Salome, S Kleeberger, B Greshake, W Zhu, C Liu, C Lippert, O Stegle, B Schölkopf, D Weigel and KM Borgwardt
    The Plant Cell, 2017, 29 (1): 5-19 (Link)
  • AraPheno: A public database for Arabidopsis thaliana phenotypes.
    Ü Seren*, DG Grimm*, J Fitz, D Weigel, M Nordborg, KM Borgwardt, A Korte
    Nucleic Acid Research (NAR), 2017, 45(D1), D1054-D1059
    * Shared first authorship (Link)

2016

  • The Genetic Architecture of Non-additive Inheritance in Arabidopsis thaliana Hybrids.
    DK Seymour*, E Chae*, DG Grimm*, CM Pizzaro, A Haeing-Müller, F Vasseur, B Rakitsch, KM Borgwardt, D Koenig and D Weigel

    Proceedings of the National Academy of Sciences (PNAS), 2016, 113 (46), E7317-E7326
    * Shared first authorship (Link)
  • Epigenomic Diversity in a Global Collection of Arabidopsis thaliana Accessions.
    Taiji Kawakatsu, Shao-shan Carol Huang, Florian Jupe, Eriko Sasaki, Robert J. Schmitz, Mark A. Urich, Rosa Castanon, Joseph R. Nery, Cesar Barragan, Yupeng He, Huaming Chen, Manu Dubin, Cheng-Ruei Lee, Congmao Wang, Felix Bemm, Claude Becker, Ryan ONeil, Ronan C. O Malley, Danjuma X. Quarless, The 1001 Genomes Consortium*, Nicholas J. Schork, Detlef Weigel, Magnus Nordborg, Joseph R.

    Cell 166.2 (2016): 492-505 (Link)
    * As part of the 1001 Genomes Consortium
  • Genomic profiles of diversification and genotype-phenotype association in island nematode lineages.
    A McGaughran, C Rödelsperger, DG Grimm, JM Meyer, E Moreno, K Morgan, M Leaver, V Serobyan, B Rakitsch, KM Borgwardt, RJ Sommer

    Molecular Biology and Evolution (2016) 33 (9): 2257-2272. (Link)
  • 1135 genomes reveal the global pattern of polymorphism in Arabidopsis thaliana.
    The 1001 Genomes Consortium*
    Cell 166.2 (2016): 481-491

    * As part pf the 1001 Genomes Consortium (Link)

2015

  • The evaluation of tools used to predict the impact of missense variants is hindered by two types of circularity.
    DG Grimm, CA Azencott, F Aicheler, U Gieraths, DG MacArthur, KE Samocha, DN Cooper, PD Stenson, MJ Daly, JW Smoller, LE Duncan and KM Borgwardt

    Human Mutation 2015, 36(5):513-523 (Link)
  • Genome-wide detection of intervals of genetic heterogeneity associated with complex traits.
    F Llinares-López, DG Grimm, DA Bodenham, U Gieraths, M Sugiyama, B Rowan, KM Borgwardt
    Bioinformatics (2015) 31(12):i303-i310 (Link)
  • Prediction of human population responses to toxic compounds by a collaborative competition.
    Eduati F, Mangravite ML, Wang T, Tang H, Bare JC, Huang R, Norman T, Kellen M, Menden PM, Yang J, Zhan X, Zhong R, Xiao G, Xia M, Abdo N, Kosyk O, NIEHS-NCATS-UNC DREAM Toxicogenetics Collaboration*, Friend S, Dearry A, Simeonov A, Tice RR, Rusyn I, Wright FA, Stolovitzky G, Xie Y, Saez-Rodriguez J
    Nature Biotechnology 2015 (Link)
    * As part of the NIEHS-NCATS-UNC DREAM Toxicogenetics Collaboration
  • Genome-wide analysis of local chromatin packing in Arabidopsis thaliana.
    C Wang, C Liu, D Roqueiro, D Grimm, R Schwab, C Becker, C Lanz, D Weigel
    Genome Research, 2015. 25: 246-256 (Link)

2014

  • Multi-task feature selection with multiple networks via maximum flows.
    M Sugiyama, CA Azencott, D Grimm, Y Kawahara and K Borgwardt
    SIAM International Conference on Data Mining (SDM 2014) (Link)

2013

  • Efficient network-guided multi-locus association mapping with graph cuts.
    CA Azencott, D Grimm, M Sugiyama, Y Kawahara and K Borgwardt
    Bioinformatics 2013, 29(13):i171-i179 (Link)
  • Accurate indel prediction using paired-end short reads.
    D Grimm*, J Hagmann*, D Koenig, D Weigel and K Borgwardt
    BMC Genomics 2013, 14:132
    * Shared first authorship (Link)
  • Geometric tree kernels: Classification of COPD from airway tree geometry.
    A Feragen, J Petersen, D Grimm, A Dirksen, JH Pedersen, K Borgwardt, M de Bruijne
    Information Processing in Medical Imaging (IPMI 2013), Lecture Notes in Computer Science Volume 7917, 171-183 (Link)

2011

  • Computational inference of difficult word boundaries in DNA languages.
    G Tsafnat, P Setzermann, D Grimm and S Partridge
    Proceedings of the 4th International Symposium on Applied Sciences in Biomedical and Communication Technologies (ISABEL 2011), ACM, New York, USA, 5 pages. (Link)